Isn’t it strange how you can sometimes look back on one particular incident -a goal,  a sending off,  a goalkeeper’s error, an injury - as the defining moment of a season’s effort. One such moment came to mind in the 42nd minute of the match at Old Trafford yesterday when Rio Ferdinand went over in a desperate bid to slide the ball away for a corner, and came up with a worried look on his face, clutching his groin.

Two minutes later, the Manchester United defender was about as mobile as a tailor’s dummy as Stuart Downing hit a low cross towards the near post and Mark Viduka dived in inches ahead of Wes Brown to head the ball past Edwin Van Der Sar for a Middlesbrough equaliser that was looking more inevitable as the game went on.

Ferdinand should not have been on the pitch at that moment. He should have been lying in the medical room, receiving vital minutes of whatever treatment they use these days to heal groin injuries. United’s army of specialist coaches should have withdrawn him immediately, sent on a replacement, re-organised, patched-up, whatever was needed to get through to half-time.

In the end, United had to settle for a point thanks to a Kieran Richardson goal in the third minute. But it wasn’t the securing of one point, but the loss of two - and the consequence of Ferdinand’s absence for at least two more weeks - that created a whole new raft of hopes and fears in London and Manchester, to say nothing of Europe.

The implications and consequences could be seismic (depending on the result of Chelsea’s visit to Newcastle) when United’s lead at the top of the Premiership will be either four points, three points, or a nerve-jangling one. But the crucial point is that United face five matches in the next 18 days, four of them away from home, and two of them in the Champions League. And they are likely to be without their entire first-choice back four for possibly one or two of these games. At this moment Gary Neville, Ferdinand, Nemanja Vidic and Patrice Evra are all on the treatment table for various injuries.

Vidic is back in training and could be back next weekend, but the danger in bringing him back too early – for the game against AC Milan on Tuesday, for instance – with Ferdinand’s departure yesterday. He came back from a similar groin strain too quickly.

Let’s have a look at the mammoth task ahead:

April 24: AC Milan at home in the CL semi-final. United hammered Roma in the quarter-finals but they’ll find Milan a totally different proposition.

April 28:
Everton away. The Blues pushing for a UEFA Cup spot next season, and manager David Moyes suing old boy Wayne Rooney over certain assertions in his new book. Tough one, this.

May 2:
AC Milan away. Make or break in United’s treble quest, and another hostile reception.

May 5:
Manchester City away. How devastating a defeat at the City of Manchester Stadium would be. It’s happened before.

May 9:
Chelsea away. Crunch time. United must hope that the entire back four are back on duty.

Chelsea’s run-in isn’t quite so daunting, but they do have the two-legged Champions League semi-final against Liverpool coming up, and they have to visit Arsenal in the Premiership, so they have problems of their own.

Then, of course, there’s always a matter of the FA Cup Final on May 19. What a mouth-watering three or four weeks we have in store – and a perfectly sound reason for those who are thinking of tinkering with the game to make it more exciting to leave it alone.

Can United overcome their problems to regain the Premiership crown? Send your views to Sportingo.